Researchers at Johns Hopkins University School of Medicine in Baltimore have found a rare, life-threatening genetic condition that affects about 1 in 10 pregnancies in the United States.
The study published online Wednesday in the Journal of Clinical Oncology found that one in every 10 pregnancies is affected.
Researchers identified the condition as a rare genetic disorder called the mitochondrial hyperoxia syndrome.
It’s a type of genetic condition caused by mutations in a gene called CpG-19.
It occurs when an enzyme called mitochrondria deacetylases a protein called Cdc16 in the mitochondria of cells.
This enzyme breaks the DNA of the mitochondrion into the chemical form of the DNA.
The condition can cause the mitochondrium to become damaged and die.
Researchers at the University of Alabama at Birmingham, led by Dr. Paul G. Schmid, believe the mitochondry disorder may have arisen because of a genetic mutation in a protein that causes mitochondria to degrade and produce excess carbon dioxide, leading to a buildup of CO 2 in the body.
The mitochondria are found in every cell in the human body, but they’re often overlooked in the clinical diagnosis.
Schmeber, a professor of pathology, has been studying mitochondrial hyperoxicosis for more than 20 years.
“We’ve been studying it as a possible cause of cancer, and this is the first time we’ve identified a mitochondrial hyperoxin in a human pregnancy,” Schmid said.
The mitochondrial hyperoxicity syndrome affects women of any age.
About a third of pregnancies have an abnormal mitochondrial hyperoxide, or a defect in the normal functioning of the mitochondrial mitochondria.
Schmet said he’s excited about finding a genetic cause of this condition in women.
“The finding that it is a rare condition is really encouraging.
This is a condition that has existed in the population for at least 20 years,” he said.
Researchers found the genetic mutation affects about 3 percent of pregnancies.
“It has not been reported in any other population before,” Schmet added.
Schmed said the mutation was not caused by any known environmental exposures.
Researchers believe the mutation could be caused by a rare environmental mutation known as the Mitochondrial X-linked recessive gene.
Mitochondria are tiny cells that make up a nucleus, or small volume, inside the cell.
The nucleus of the cell contains the genetic material of the cells surrounding it.
This nucleus is what gives the mitochondric body its energy.
It also contains the genes and instructions for making mitochondria, a complex machinery that makes proteins, enzymes and DNA.
Schmel said the mitochondrial X-chromosome is part of the normal genetic sequence.
Researchers think that the mutation occurred when an individual had a mutation in the Mitoc-X gene, which codes for a protein in the nucleus that’s required for mitochondrial function.
The mutation caused the mitochondrons to become defective, which led to their breakdown.
“There are a number of genes that play a role in mitochondrial function, and Mitoc X has been shown to be one of them,” Schmed added.
“So we think that MitocX could have a role to play in this genetic defect that causes mitochondrial hyperOXia.”
Researchers hope to learn more about the mitochondrial dysfunctions caused by the mutation in more people in the future.
In addition to the study, Schmet and colleagues will continue their study to identify other rare genetic disorders affecting pregnancies.
Researchers hope that this finding will provide insight into how and why some people are more likely to be affected by these genetic conditions.